Cancer Overview
A comprehensive foundation for understanding cancer, navigating your diagnosis, and empowering your journey toward recovery.
Not just One Disease
Did you know that cancer is not just one disease? Indeed, as there are over 200 different types of cancer that can affect individuals.
The Analogy of Care
To illustrate, when experiencing chest pain, the underlying reasons could be a heart attack, a lung infection, indigestion, or a broken rib cage. These are all distinct medical conditions that require different treatments.
"Similarly, how two different chest pains are not indicative of the same medical problem, likewise two different types of cancers are unique and require different treatments."
Therefore, it’s crucial not to accept everything you hear from other people with cancer since each person’s situation is different.
Core Knowledge
Essential Clinical Perspectives
Major Categories
Carcinomas
Begin in skin or tissues lining internal organs.
Sarcomas
Begin in bone, cartilage, or muscle tissue.
Leukemias
Begin in blood-forming tissue like marrow.
Lymphomas
Begin in the immune system cells.
Understanding Staging
Stage 0
Abnormal cells present but not yet spread.
Stages I-III
Cancer is present; higher numbers = larger tumor.
Stage IV
The cancer has spread to distant body parts.
Common Symptoms
Persistent Fatigue
Tiredness that doesn't improve with rest.
Unexplained Pain
New, persistent pain with no clear cause.
Skin Changes
New moles or changes in existing ones.
Weight Loss
Losing 10+ pounds for no apparent reason.
Risk Factors
Lifestyle
Smoking, diet, and physical activity levels.
Environment
Exposure to radiation or certain chemicals.
Genetics
Inherited mutations passed through families.

Simple View
about Cancer
Cells are the building blocks of our body. They grow and divide to create new cells, ensuring the body functions properly. However, when genetic changes (mistakes or changes in the DNA) interfere, cells may stop following normal rules.

The Tumor
This interference can trigger uncontrollable growth of damaged cells, leading to the development of cancer and the formation of a tumor.
Malignant
Meaning the tumor is cancerous; it can grow and spread to other parts of the body.
Benign
Meaning the tumor can grow, but will not spread to other parts of the body.
Main Categories
Distinct Biological Paths
Hematologic (Blood) Cancers
Cancers of the blood cells. For example: leukemia, lymphoma, and multiple melanoma.
Solid Tumor Cancers
Cancers of any of the other body organs or tissues. For example: breast, prostate, lung, and colorectal cancers.
The Cancer’s Stage
When found, tests are done to see how big the cancer is and whether it has spread from where it started.
1 or 2
Means that the cancer has not spread very much.
3 or 4
Means it has spread more extensively across the body.
"The stage of the cancer is very important in choosing the best treatment for a person. Ask your doctor about your stage and what it means for you."
Common Symptoms
Cancer can happen with various symptoms, and the specific signs depend on the type and stage.
Significant Weight Loss
Significant and unintentional weight loss.
Persistent Fatigue
A state of extreme tiredness or exhaustion, both physically and mentally that doesn’t improve with rest.
Fever
Fever that occurs mostly at night.
Skin Changes
Changes in the colour, size, shape, or thickness of moles or the appearance of new skin abnormalities.
Easy Bleeding
Bruising or bleeding more easily.
Lumps or Bumps
Lumps or bumps under your skin that don’t go away.
“Persistent or unusual symptoms should always be evaluated by a healthcare professional.”
Many of these symptoms can also be caused by non-cancerous conditions.
General
Risk Factors
Having risk factors doesn’t guarantee you’ll get cancer. Some people with many risk factors never get it, while others with no known risks do.
History
A personal or family history of cancer.
Body Weight
Carrying too much weight, known as being overweight or obese.
Viral Infections
Some types of viral infections, such as human papillomavirus (HPV) and the hepatitis virus.
Radiation
Exposure to radiation, including ultraviolet radiation from the sun.
"It’s crucial to know your risk factors and discuss them with your healthcare team. This information helps you make choices for better health."
Registry Guide • 2026
Deep Dive
Technical ReferenceFigures

Mechanism of cell division in malignant growth
